The fascinating history of insulin
This year marks 100 years since the administration of the first insulin injection, the discovery of insulin (101 years ago) representing a cornerstone in the history of medicine. This moment transformed insulin-dependent diabetes from a certain death sentence into a chronic condition associated with a high life expectancy. Tens of millions of lives or more have been saved this way. The Romanian Nicolae Paulescu contributed decisively to the discovery of insulin in 1921. In early 1922, Banting and Best administered insulin to humans for the first time, to Leonard Thompson – a 14-year-old child, his health improving considerably after the administration of purified insulin, by the Canadian team. In the same year, insulin production began in Indianapolis, later expanding throughout the world. In 1923, the Nobel Prize for Physiology or Medicine was awarded to Banting and MacLeod, for the discovery of insulin, but great controversies were triggered, not extinguished to this day. In an attempt to calm the spirits, Banting shared his prize with Best and Macleod with Collip. However, Paulescu remained excluded and died full of bitterness, being unable to accept the fact that fraud can also occur in science.