Prevalence of syndrome Z among coronary artery disease patients attending a tertiary care hospital in south India

  • Narghis Bushra, Dr 1. department of physiology, shri sathya sai medical college and research institute, ammapettai, affiliated to sri balaji vidyapeeth university, pondicherry, india
  • Damal Chandrasekhar Mathangi, Dr 1. Department of Mind, Body, Medicine and Lifestyle Sciences, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, India https://orcid.org/0000-0002-3148-3792
  • Nayar Pradeep, Dr Fortis Malar Hospital, Chennai, Tamilnadu, India
  • Remya Krishnan Jyothi 7845479071 https://orcid.org/0000-0001-9788-1198
Keywords: coronary artery disease., Obstructive sleep apnea, Metabolic syndrome, Syndrome Z

Abstract

Abstract

Introduction:

Metabolic Syndrome (MS) and Obstructive Sleep Apnea (OSA) triggers the development of Coronary Artery Disease (CAD). This study aims to estimate the prevalence of syndrome Z (Metabolic syndrome + Obstructive Sleep Apnea) among CAD patients

Materials and Methods: OSA was assessed based on modified Berlin questionnaire and metabolic syndrome was identified based on National Cholesterol Education Program Adult Treatment Panel III guidelines. Anthropometric assessment and blood pressure were recorded. Serum triglyceride, high density lipoprotein level (HDL) and fasting blood glucose levels were estimated.

Results:

Syndrome Z was prevalent among 51% of CAD subjects. The other groups were CAD only, CAD with MS and CAD with OSA. All data were compared using one-way ANOVA followed by Tukey’s multiple comparison. Blood pressure, triglyceride and HDL showed significant F test ratio. Post hoc test showed CAD subjects with syndrome Z had significantly higher mean levels of systolic BP (140.30± 17.94) (p=0.001), diastolic BP (89.09± 11.82) (p=0.003), triglyceride (232.73± 107.71) (p=0.000) and HDL levels (33.22± 6.46) (p=0.000) compared to other groups.

Conclusion:

Concurrent presence of OSA and MS has adverse cardio-metabolic outcome. Identifying the presence of OSA and appropriate treatment at early stages can prevent the development of CAD to an extent

Author Biographies

Narghis Bushra, Dr, 1. department of physiology, shri sathya sai medical college and research institute, ammapettai, affiliated to sri balaji vidyapeeth university, pondicherry, india

Tutor

Department of Physiology

 

Damal Chandrasekhar Mathangi, Dr, 1. Department of Mind, Body, Medicine and Lifestyle Sciences, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, India

Professor and Head of the Department

Nayar Pradeep, Dr, Fortis Malar Hospital, Chennai, Tamilnadu, India

Senior Consultant Cardiologist

Remya Krishnan Jyothi, 7845479071

Associate Professor

Department of Physiology

Shri Sathya Sai Medical College & Research Institute, Ammapettai, Tamil nadu

Affiliated to Sri Balaji Vidyapeeth University, Puducherry, India

Published
2022-03-28
How to Cite
Bushra, Narghis, Damal Mathangi, Nayar Pradeep, and Remya Krishnan Jyothi. 2022. “Prevalence of Syndrome Z Among Coronary Artery Disease Patients Attending a Tertiary Care Hospital in South India”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 29 (1), 16-21. https://rjdnmd.org/index.php/RJDNMD/article/view/1041.