LIVER AND METABOLIC DISEASES

  • Ramona Maria Drăguț
  • Emilia Rusu
  • Georgiana Enache
  • Horațiu Popescu
  • Raluca Nan
  • Gabriela Radulian
Keywords: Chronic liver diseases, insulin resistance, metabolic disorders, adipocytokine

Abstract

Chronic liver diseases and metabolic disorders represent two real public health problems that cause increased morbidity and mortality in a significant number of people worldwide. The most common cause of chronic liver disease is represented by non- alcoholic fatty liver disease (NAFLD). Hepatic inflammation is a critical event in the progression of NAFLD and excess adiposity, through the hormones and cytokines secreted by the adipose tissue, plays an important role. There is ample evidence supporting a significant association between chronic hepatitis C (CHC) and metabolic disorders. CHC may be considered not just a viral disease, but also a metabolic type condition. Multiple pathogenic mechanisms have been proposed to explain the interaction between hepatitis C virus and impairment of glucose and lipid metabolism and diabetes. The relationship between hepatitis B infection (HBV) and metabolic diseases remains uncertain.

Published
2016-03-15
How to Cite
Drăguț, Ramona, Emilia Rusu, Georgiana Enache, Horațiu Popescu, Raluca Nan, and Gabriela Radulian. 2016. “LIVER AND METABOLIC DISEASES”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 23 (1), 105-12. https://rjdnmd.org/index.php/RJDNMD/article/view/112.
Section
Review Articles