The state of genital microbiocenosis in women with functional ovarian cysts on the background of type 2 diabetes mellitus

Olga Sergeevna Shapoval; Michael Ivanovich Sheremet

Olga Sergeevna Shapoval Department of Gynecology, Zaporizhian Medical Academy of Postgraduate Education of the Ministry of Healthcare of Ukrain, Zaporizhia, Ukraine
Michael Ivanovich Sheremet Surgery Department No. 1, Bukovinian State Medical University, Chernivtsi, Ukraine

Keywords: type 2 diabetes mellitus, functional ovarian cysts, microbiocenosis

Abstract

The aim of the work is to study the state of genital biocenosis in women with functional ovarian cysts on the background of type 2 diabetes mellitus. Sixty patients of reproductive age with functional ovarian cysts and type 2 diabetes mellitus were examined in the Department of Gynecology in the Limited liability company “VITACENTER”. The control group was represented by 50 healthy non-pregnant women. General clinical, ultrasound examination of pelvic organs and bacteriological and molecular genetic study of discharge from the genital tract was carried out. The survey found in 40–65% of patients the activation of their own conditionally pathogenic flora. There were diagnosed 25% cases of normocenosis of the vagina and 75% cases of dysbiosis of the vagina. Qualitative and quantitative assessment of the microbiome of the genital tract is fundamentally necessary for understanding the strategy of treatment of pathological conditions in gynecological practice. The spectrum of the most aggressive microflora prevailed in patients with infertility, which contributed to the reduction of nonspecific reactivity and the maintenance of the existing inflammatory process.