The association between ABO/RH blood groups and type 2 diabetes mellitus in Dhamar Governorate, Yemen
The literature shows that ABO blood groups and demographic characteristics influence susceptibility to type 2 diabetes mellitus (T2DM) and may be used to stem the rising incidence of the disease. However, these associations vary geographically, which necessitates the need to determine the association in every locality. So far, no study has been performed in Dhmar Governorate to look for the association of diabetes mellitus (DM) with blood groups. We studied the association of ABO blood groups with type 2 diabetes mellitus. This study was conducted in Dhamar Governorate from February to May 2022. The study included 332 people, including patients diagnosed with type 2 diabetes and healthy controls. All participants were examined for ABO and Rh by a slide test method. In addition, sociodemographic and clinical data were collected with a semi-structured pretested questionnaire. The questionnaire included clear questions to collect the relevant data. The order of prevalence of diabetes mellitus noted in the blood group types were O, A, B and AB, respectively. The maximum prevalence of type 2 diabetes mellitus was noted with the O+ blood group at 39.5% and the least with the blood group AB- at 0.6%. There was a significant association between A and O blood groups and the risk of developing T2DM. The present work confirms that blood group A is an alarming risk factor for susceptibility to T2DM.