Vitamin D status: approaches to diagnosis and prevention in pregnant women at high risk of moderate preeclampsia
Abstract
Vitamin D deficiency is common, and there is a huge gap between the recommended dietary intake of vitamin D and low vitamin D stores in the general population. The aim of the study was to study the characteristics of vitamin D status and its effect on the course of pregnancy in patients at high risk of developing preeclampsia. In accordance with the set goal, 68 pregnant women were examined at a gestation period of 10–12 weeks. Group I included 30 pregnant women who had a high risk of developing preeclampsia and had vitamin D deficiency. Group II consisted of 18 pregnant women with a high risk of developing preeclampsia and vitamin D deficiency. Group III consisted of 20 somatically healthy pregnant women with normal levels of 25 – -hydroxycholecalciferol. The course of pregnancy in the studied groups was characterized by hemodynamic disturbances in the uterine arteries in 23.3% of pregnant women of the first group of the study and in 27.7% of the patients of the second group. In 3.33% of patients of the first group, pregnancy was complicated by premature detachment of the normally located placenta, and in 5.5% of the second group, respectively. The importance of determining the concentration of vitamin D during pregnancy for the timely prevention of obstetric and perinatal complications was investigated. It is recommended to use 2000 IU of vitamin D for pregnant women with a deficient level of this vitamin for a favorable course of pregnancy and childbirth for patients who are at high risk of developing moderate preeclampsia.