A case series of epulides in diabetic and non-diabetic patients: is there a link?

Abstract

The epulis is a tumor caused by the chronic irritation or trauma of restorations, of any sharp and overhanging edges of crowns/bridges, or mobile prostheses, found mostly in the buccal side of the gingiva and interdental papillae. It appears like a sessile lesion with a smooth or ulcerated surface. The main scope of this study is to show some clinical and histological features of epulides from patients suffering or not from diabetes mellitus. The study is a series of 15 cases of patients with and without diabetes melitus. The diagnosis of epulis was made by an oral medicine specialist based on clinical and histopathological features. In most cases, the epulides were located on the buccal side of the gingiva and near an irritating factor (dental crowns or bridges). The most frequent histopathological diagnosis was the fibrous pattern with abundant chronic perivascular and interstitial lymphoplasmacytic infiltrate covered by acanthotic non-keratinized stratified squamous epithelium.