Physiological assessment of the biomarker’s atrial natriuretic peptides and cardiac troponins in patients with type 2 diabetes
Abstract
Diabetes is considered a chronic metabolic disease characterized by elevated glucose levels due to either complete or relative deficiency of insulin hormone or the existence of factors antagonizing insulin action. Biomarkers are molecular, biochemical, physiological, anatomical elements, or imaging features that can be used for accurate diagnosis, disease progression assessment, prediction and monitoring of treatment effects, and determination of disease severity. This study investigated the association between two biomarkers, Atrial Natriuretic Peptides (ANP) and Cardiac Troponins (CT), and heart disease risk in diabetic women. Blood samples were collected from diabetic and healthy women, and ANP and CT levels were measured using ELISA. Diabetic women exhibited significantly higher ANP levels, potentially attributed to factors like hyperinsulinemia and elevated blood sugar. ANP is involved in cardiovascular disease development. CT levels were also significantly elevated in diabetic women and linked to vascular calcification and inflammation. ANP and CT may serve as valuable biomarkers for assessing heart disease risk in diabetic women, indicating vascular damage and inflammation. Further research is needed to validate these findings and explore their predictive value for specific cardiovascular diseases. These biomarkers show potential as early diagnostic predictors of heart diseases in diabetic women, warranting further investigation for clinical applications.