Nutrigenomics and Diabetes Mellitus

Smrithy Sivadas; Renita Lorina Castelino; Vidya Ajila; Yashika Jain

Smrithy Sivadas Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India
Renita Lorina Castelino Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India
Vidya Ajila Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India
Yashika Jain Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India

Keywords: nutrigenomics, Diabetes Mellitus, nutrition, genetics

Abstract

Technical insight has linked the genetic buildup of an individual with the protective role of nutrients, thereby aiming to increase patients’ quality of life. Because nutrition has been linked to several inflammatory diseases and conditions, such as Type 2 diabetes, cardiovascular disease, rheumatoid arthritis, and inflammatory bowel disease, recent studies have focussed on the combination of nutrition along with genetics paving the way to the development of the modality “Nutrigenomics”.With the prevalence of Diabetes Mellitus [DM] increasing globally at an alarming rate, it has become a major health concern of the worldwide population. The predisposition of an individual to DM is partly contributed by genetics and, to a larger extent, is influenced by the changing dietary environment. Nutrigenomics has the potential to advance the prevention and therapy of diet-related disorders like DM by contributing to a genetic angle of view along with the nutritional counterpart. This review focuses on the genetic and nutrient microenvironment, bridging the two disciplines and forecasting its influence on DM.