Inhibin-A as an early marker of moderate preeclampsia development: Complex modified therapy and its impact on placental structure

Abstract

Hypertensive disorders during pregnancy are a significant issue in modern obstetrics. Preeclampsia complicates approximately 5% of all pregnancies worldwide. It is an important cause of complications for the mother, fetus, and newborn and can also lead to fatal consequences. Gestosis is a critical condition syndrome that occurs during pregnancy, based on a variety of sequentially developed organ dysfunctions due to insufficient perfusion-metabolic processes and the development of fetal egg structures. Gestosis, as a syndrome of multiple organ dysfunction, is necessarily associated with pregnancy and is a critical condition. Specifically, dysfunctions are not incapacity, as dysfunction is a broader concept of organ function disruption, which can be both hypo- and hyperdynamic in nature. Also, there is not enough data on late gestosis in the modern literature which supports the relevance of the diagnosis problem and choosing the optimal treatment strategy for such women. All this leads to a growing interest in the pathogenesis of this problem.