The predictive utility of one-hour plasma glucose in oral glucose tolerance test: A study of 231 nondiabetic patients
Abstract
This study aims to assess the predictive value of one-hour plasma glucose levels (1h-PG) in identifying high-risk individuals for type 2 diabetes mellitus (T2DM) among nondiabetic patients. A prospective analysis was conducted on 231 patients at Constanța Emergency Hospital, using Oral Glucose Tolerance Tests (OGTT) with measurements at 0, 30, 60, and 120 minutes. The 1h-PG was compared with fasting plasma glucose (FPG) and 2-hour plasma glucose (2h-PG) to determine its diagnostic sensitivity and utility in screening for prediabetes and diabetes. Our findings, supported by recent studies, indicate that 1h-PG offers greater sensitivity in detecting early dysglycemia compared to traditional measures. Targeted early screening can reduce the incidence of diabetes-related complications.