The predictive utility of one-hour plasma glucose in oral glucose tolerance test: A study of 231 nondiabetic patients

  • Florin Gabriel Panculescu Department of Diabetes and Nutrition Diseases, Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania
  • Doina Catrinoiu Department of Diabetes and Nutrition Diseases, Emergency County Hospital of Constanta, Constanta, Romania
  • Cristina Maria Mihai Department of Pediatrics, Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania
  • Tatiana Chisnoiu Department of Pediatrics, Emergency County Hospital of Constanta, Constanta, Romania
Keywords: one-hour plasma glucose, type 2 diabetes mellitus, prediabetes, early screening

Abstract

This study aims to assess the predictive value of one-hour plasma glucose levels (1h-PG) in identifying high-risk individuals for type 2 diabetes mellitus (T2DM) among nondiabetic patients. A prospective analysis was conducted on 231 patients at Constanța Emergency Hospital, using Oral Glucose Tolerance Tests (OGTT) with measurements at 0, 30, 60, and 120 minutes. The 1h-PG was compared with fasting plasma glucose (FPG) and 2-hour plasma glucose (2h-PG) to determine its diagnostic sensitivity and utility in screening for prediabetes and diabetes. Our findings, supported by recent studies, indicate that 1h-PG offers greater sensitivity in detecting early dysglycemia compared to traditional measures. Targeted early screening can reduce the incidence of diabetes-related complications.

Published
2024-12-16
How to Cite
Panculescu, Florin Gabriel, Doina Catrinoiu, Cristina Mihai, and Tatiana Chisnoiu. 2024. “The Predictive Utility of One-Hour Plasma Glucose in Oral Glucose Tolerance Test: A Study of 231 Nondiabetic Patients”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 31 (4), 404-10. https://rjdnmd.org/index.php/RJDNMD/article/view/1787.