EVALUATION OF UNSTIMULATED SALIVA LEVELS IN CONTROLLED AND UNCONTROLLED TYPE 2 DIABETES MELLITUS

Maryam Jalili Sadrabad; Seyed Habibollah Hashemian; Zahra Hayati; Raheb Ghorbani; Shabnam Sohanian

Maryam Jalili Sadrabad Assistant Professor, Oral Medicine Department, Dental School ,Semnan University of Medical Science, Semnan, Iran.
Seyed Habibollah Hashemian Dentistry Student, Student Research Committee, Dental School, Semnan University of Medical Sciences, Semnan, Iran.
Zahra Hayati Assistant Professor, Oral Medicine Department, Dental School ,Semnan University of Medical Science, Semnan, Iran.
Raheb Ghorbani Full Professor, Department of Epidemiology & Statistics, Faculty of Medicine, Semnan University of Medical science, Semnan, Iran.
Shabnam Sohanian 5. Assistant Professor, Oral and Maxillofacial Pathology Department, Dental School, Semnan University of Medical Science, Semnan, Iran.

Keywords: Diabetes Mellitus, Type 2 Diabetes, Saliva, Unstimulated Saliva, HbA1C

Abstract

Introduction: Diabetes is a common syndrome characterized by a steady rise in blood glucose levels and has various side effects, including oral complications such as periodontitis and dry mouth. Material and Methods: This case-control study was performed on 30 patients with type 2 diabetes mellitus and 30 normal people who were referred to Kowsar Hospital of Semnan, Iran. The study groups were evaluated for HbA1C, and unstimulated saliva and data were statistically analyzed. Results: Unstimulated saliva in diabetic patients was 0.02 ± 0.07 ml/ min and ± 14.0 ± 02.0 ml in the control group (P <0.001). In the diabetic group, 18 out of the 30 diabetic patients (60%) had uncontrolled glucose (HbA1c was 7% or higher), and the rest had controlled glucose. According to the HbA1c study, the mean standard deviation of unstimulated saliva in controlled diabetic patients was 0.08 0 ± 0.02 ml/min and 0.06 ± 0.02 ml/min in uncontrolled patients, which showed a significant difference (p=0.006). Conclusion: Dry mouth was more prevalent in people with uncontrolled diabetes, so blood glucose level and its control had a significant effect on the reduction of unstimulated salivation.