Association between night eating syndrome in overweight and obese children 10-17 years of age and dyslipidemia

Abstract

Background and Aims: Night eating syndrome (NES) is one of the reasons for increased prevalence of obesity. Nevertheless, there is lack of knowledge about the influence of NES on lipid metabolism in children. The objective of the study was to determine the influence of NES on the lipid profile in overweight and obese children 10–17 years of age. Material and Method: A population of 110 children with excess weight and obesity was enrolled in the study. NES was diagnosed based on existing criteria. Anthropometric measurements were performed for all participants. Lipid profile assessments included detection of TC, HDL-C, and TG with an enzymatic method and formula assessment for LDL-C, VLDL-C, and non-HDL-C levels. Results: NES was diagnosed in 21.82% of children. Dyslipidemia was detected in 70.83% of children with NES and in 44.19% subjects in the group without NES (p = 0.04). Atherogenic level of HDL-C was diagnosed in 45.83% subjects with NES compared with children without NES 15.12% (p = 0.001). Multivariate regression analysis has found significant association between NES and evidence of dyslipidemia and HDL-C level in the population of obese and overweight children (p < 0.05). Conclusions: NES is one of the reasons for changes in lipid profile in children; therefore, screening for eating disorders in overweight and obese children must be implemented in routine practice to reduce the risk of dyslipidemia and its consequences.