RELATIONS BETWEEN DIABETES, KIDNEY DISEASE AND METABOLIC SYNDROME: DANGEROUS LIAISONS

  • Alin Albai
  • Mirela Frandes
  • Ramona Luminita Sandu
  • Gabriel Spoiala
  • Flavia Hristodorescu
  • Bogdan Timar
  • Romulus Timar
Keywords: diabetes mellitus, chronic kidney disease, hypertension, hyperlipidemia, Framingham risk score

Abstract

Background and aims: Diabetes mellitus is the disease-challenge of our century, characterized by an increase in serum glycemia, which may lead to the occurrence of micro- and macro-vascular complications with serious consequences on both patient and public health. The Framingham risk score was obtained from a complex study and it estimates the individual risk of each patient to develop a cardiovascular event over the next 10 years depending on certain parameters (age, smoking, total cholesterol, HDLcholesterol, systolic blood pressure). Our study main aim was to evaluate the crossassociations between the components of the metabolic syndrome, cardiovascular risk, diabetes-related biological parameters and chronic kidney disease in patients hospitalized due to poor metabolic control. Material and methods: In this cross-sectional study, we enrolled 218 patients with type 2 diabetes, admitted in the Diabetes Clinic of the “Pius Brinzeu” Emergency Hospital Timisoara according to a consecutive-case population-based principle. Results: We observed that the quality of the glycemic control is impaired in patients with higher age; the body mass index was positively correlated with HbA1c and hypertension accompanies diabetes in more than half of the cases. Moreover, we observed that high levels of LDL cholesterol are significantly correlated with high levels of HbA1c. Conclusions: There was poor metabolic control in patients with associated complications such as hyperlipidemia, cardiovascular disease or chronic kidney diseases. Also, in most of the cases  hypertension was associated with type 2 diabetes mellitus.

Published
2017-12-16
How to Cite
Albai, Alin, Mirela Frandes, Ramona Sandu, Gabriel Spoiala, Flavia Hristodorescu, Bogdan Timar, and Romulus Timar. 2017. “RELATIONS BETWEEN DIABETES, KIDNEY DISEASE AND METABOLIC SYNDROME: DANGEROUS LIAISONS”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 24 (4), 355-62. http://rjdnmd.org/index.php/RJDNMD/article/view/24.
Section
Original Research Articles