A DIFFERENT VIEW TO OLDER DIABETICS: MANAGEMENT OF TREATMENT ACCORDING TO COGNITIVE FUNCTIONS

  • Remzi Bahşi Ankara University School of Medicine, Department of Geriatrics
  • Deniz Mut Sürmeli
  • Tuğba Turgut
  • Hande Selvi Öztorun
  • Volkan Atmış
  • Ahmet Yalçın
  • Sevgi Aras
  • Murat Varlı
Keywords: diabetes mellitus; cognitive impairment; dementia

Abstract

Background: Diabetes Mellitus is a chronic systemic disease which has multiple complications and the presence of these complications affects the management of disease. It is also important to consider cognitive functions when managing the treatment of older diabetics. In this study, we aimed to make proposals for the appropriate drug choice to preserve cognitive functions in elderly diabetics. Methods: A total of 270 older diabetic patients were reviewed. Possible risk factors of cognitive impairment were investigated. Correlation analysis was performed between MMSE and GDS, age, HbA1c, duration of diabetes. Results: Sulfonylurea (adj. OR: 2.33, %95 CI: 1.11- 4.90) and insulin treatment (adj. OR: 3.79, %95 CI: 1.56-9.21) were found associated with increased risk of cognitive impairment. In addition, there was a negative correlation between MMSE and GDS (r: -.129, p<0.05). Conclusion: We suggest that insulin and sulfanylureas should be used with caution in those with cognitive impairment.

Published
2019-10-22
How to Cite
Bahşi, Remzi, Deniz Mut Sürmeli, Tuğba Turgut, Hande Selvi Öztorun, Volkan Atmış, Ahmet Yalçın, Sevgi Aras, and Murat Varlı. 2019. “A DIFFERENT VIEW TO OLDER DIABETICS: MANAGEMENT OF TREATMENT ACCORDING TO COGNITIVE FUNCTIONS”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 26 (3), 235-41. http://rjdnmd.org/index.php/RJDNMD/article/view/620.
Section
Original Research Articles