Correlation of Glycated Hemoglobin and Glucose levels after Oral Glucose Tolerance test in gestational diabetes patients: A Cross Sectional study

  • Anuradha Shankar, Dr Department of Biochemistry, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Kanchipuram District, TamilNadu-603103, India
  • D.V. Satya Murthy G, Dr Department of Biochemistry, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Kanchipuram District, TamilNadu-603103, India http://orcid.org/0000-0001-6678-0001
  • Sumathy S, Dr sandeep
  • Santhini Gopalakrishnan S, Dr. Department of Biochemistry, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Kanchipuram District, TamilNadu-603103, India
Keywords: gESTATIONAL DIABETES MELLITUS, Glycated hemoglobin

Abstract

Abstract :

Gestational diabetes mellitus (GDM) is a prevalent and potentially serious condition which may put both mothers and neonates at risk. The current recommendation for diagnosis is the oral glucose tolerance test (OGTT). OGTT is a cumbersome test that is time consuming.So we want to test the utility of HbA1c as a screening tool in pregnancy for Gestational Diabetes mellitus. Aim: This study aimed to determine the usefulness of HbA1c test as a diagnostic tool for GDM as compared to the traditional criteria based on the OGTT. Materials and methods: This study was done among 156 pregnant women of the age group of 20-40 yrs with gestational period of 24-28weeks attending the Obstetrics and Gynecology OPD of Chettinad Hospital and research institute, Chengalpattu from July 2019 to December 2019.Results: The HbA1c values will be correlated with OGTT values using Pearsons correlation analysis and there was significant correlation between HbA1c and post glucose values.(p valu<0.05).ROC curve analysis done for HbA1c showed an area under the curve of 0.569. Conclusion: HbA1c may have a role in the diagnosis of GDM, but further studies among large populations might be required to approve the use of HbA1c instead of OGTT in the diagnosis of GDM.

Key words: Gestational diabetes mellitus;Glycate hemoglobin;OGTT

Author Biographies

Anuradha Shankar, Dr, Department of Biochemistry, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Kanchipuram District, TamilNadu-603103, India

Associate professor,Department of Biocehmistry,CARE

D.V. Satya Murthy G, Dr, Department of Biochemistry, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Kanchipuram District, TamilNadu-603103, India

Associate Professor,Department of BIOCHEMISTRY,CARE

Sumathy S, Dr, sandeep

pROF&HOD ,Deaprtment of Biochemistry,CARE

Published
2021-06-30
How to Cite
Shankar, Anuradha, D.V. Satya Murthy G, Sumathy S, and Santhini Gopalakrishnan S. 2021. “Correlation of Glycated Hemoglobin and Glucose Levels After Oral Glucose Tolerance Test in Gestational Diabetes Patients: A Cross Sectional Study”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 28 (2), 137-41. http://rjdnmd.org/index.php/RJDNMD/article/view/931.