Association between glycated hemoglobin and vitamin D levels in type 2 diabetes mellitus
Background and Aims: Type 2 Diabetes Mellitus (T2DM) is one of the most common chronic disorders, affecting millions of people around the world. Vitamin D may enhance secretion of insulin from the beta cells of pancreas, increase glucose uptake by the peripheries and decrease systemic inflammation. Hence the study aims to find out the role of vitamin D deficiency in pathogenesis of diabetes mellitus.
Materials and Methods: A total of 52 T2DM patients were included in the study. The mean level of vitamin D and Glycated Hemoglobin (HbA1c) were assessed. Fundoscopic evidence was collected to look for evidence of diabetic retinopathy. For that routine urine check was done to look for evidence of proteinuria, which indicating diabetic nephropathy. Statistical analysis was done using SPSS software.
Conclusion: Our study indicated that there is an inverse relationship between HbA1c and serum Vitamin D levels in diabetics. There is increase in the micro vascular complications of T2DM with decrease in vitamin D levels.