Assessment of quality of life in women with combined gynecological pathology

Viktoriia Martyniuk; Larysa Malanchuk; Iryna Malanchyn; Ulyana Franchuk

Viktoriia Martyniuk Department of Obstetrics and Gynaecology No.1, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine
Larysa Malanchuk Department of Obstetrics and Gynaecology No.1, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine
Iryna Malanchyn Department of Obstetrics and Gynaecology No.1, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine
Ulyana Franchuk Department of Obstetrics and Gynaecology No.1, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine

Keywords: genital endometriosis, fibrocystic mastopathy, quality of life

Abstract

Despite the centuries-old history of studying various aspects of endometriosis, this disease remains a central medical and social problem. Endometriosis is a widespread pathology that affects 10 to 30% of reproductive-aged women, causing reproductive function failure, invalidism, and inferiority complex. The aim of this study is to determine the level of quality of life in women with combined gynecological pathology. The clinical part of the work was carried out at the Ternopil regional clinical perinatal center “Mother and Child”. The study included 102 patients with genital endometriosis, aged from 27 to 45 years. Adenomyosis and fibrocystic mastopathy diagnosis was based on complaints, medical history, objective data, gynecological examination, and instrumental examination. The research groups were formed taking into account the polymorphism of genes in the detoxification system. Group I included 75 individuals with GSTT1del and GSTM1del. Group II consisted of 27 individuals who did not have deletions in both phase II detoxification system genes. According to our observations, these diseases significantly determine the indicators of the quality of life of sick women, which requires new approaches to the treatment of such patients in order to reduce the reproductive potential of the nation.