USE OF METFORMIN IN PEDIATRIC TYPE 2 DIABETES
Keywords:
type 2 diabetes mellitus, children/adolescents, metformin
Abstract
In the last 10 years the incidence of type 2 diabetes (T2DM) in children and adolescents has increased, due to increasing prevalence of obesity in youth. Therefore, the prevalence of diabetes-related complications such as hypertension, hyperlipidemia and microalbuminuria has also increased in pediatric T2DM. The pathogenesis of T2DM in children involves genetic and environmental factors that will determine the increase of insulin resistance and decrease of beta pancreatic insulin secretion. Only metformin and insulin are approved for clinical use in children in the majority of countries. The aim of this paper is to review the benefits of the treatment with metformin in children and adolescents with T2DM.
Published
2013-12-15
How to Cite
Paun, Diana, Alexandra Bulgar, Andreea Brehar, and Rucsandra Dănciulescu Miulescu. 2013. “USE OF METFORMIN IN PEDIATRIC TYPE 2 DIABETES”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 20 (4), 435-39. https://rjdnmd.org/index.php/RJDNMD/article/view/213.
Issue
Section
Review Articles