MULTIFACTORIAL ANALYSIS OF A GROUP OF PREDIABETES PATIENTS IN TERMS OF CARDIOVASCULAR RISK

  • Eduard Adamescu
  • Cătălina Niculescu
  • Carmen Dobjanschi
Keywords: prediabetes, IFG, IGT, cardiovascular risk

Abstract

Background and Aims: “Prediabetes” is defined by Impaired Fasting Glucose (IFG) or Impaired Glucose Tolerance (IGT), both states associated with increased risk for diabetes and high cardiovascular (CV) risk. The aim of our study was to investigate a population with prediabetes compared to a group from the general population in respect with the risk for progression to diabetes and CV risk parameters. Materials and Methods: We investigated 124 ambulatory patients with prediabetes and 98 persons without any known metabolic disorders (control group), for CV risk parameters and risk of developing diabetes. Results: We found statistically significant differences (p <0.05) for average weight, waist, BMI and lipids between the two groups. We also found a double risk score of developing diabetes in prediabetes patients compared to the control group. No significant differences were found in terms of anthropometric parameters, lipid values, cardiovascular disease and diabetes risk score for the IFG, IGT and IFG + IGT subgroups. Conclusions: People with prediabetes have features that differentiate them from the general population, both in terms of the history, anthropometric and biochemical characteristics. Increased risk for progression to diabetes, but also highly increased CV risk makes very useful the prevention efforts focused on this population group.

Published
2013-03-15
How to Cite
Adamescu, Eduard, Cătălina Niculescu, and Carmen Dobjanschi. 2013. “MULTIFACTORIAL ANALYSIS OF A GROUP OF PREDIABETES PATIENTS IN TERMS OF CARDIOVASCULAR RISK”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 20 (1), 29-36. https://rjdnmd.org/index.php/RJDNMD/article/view/241.
Section
Original Research Articles