MANAGEMENT OF HYPERTENSION IN DIABETIC PATIENTS WITH CHRONIC KIDNEY DISEASE

Abstract

Diabetes mellitus and hypertension are the most common causes of end-stage renal disease. Blood pressure goals in patients with diabetic kidney disease are <130/80 mmHg. The first line therapy for hypertension in these patients are the angiotensin-converting enzyme inhibitors and/or the angiotensin II receptor blockers. These drugs delay the onset of microalbuminuria, retard progression from microalbuminuria to macroalbuminuria, reduce the urinary albumin-creatinine ratio and improve glomerular filtration rate.