GLUCOSE VARIABILITY IN PERSONS WITH DIABETES EVALUATED BY CONTINUOUS GLUCOSE MONITORING
Blood glucose level is the main indicator of diabetes control. It is related to diabetes evolution and appearance of chronic complications. Daily and/or postprandial glucose fluctuations induce oxidative stress and endothelial dysfunction in a higher extent than sustained hyperglycemia. Glucose excursions can be expressed by glucose variability and by mean amplitude of glucose excursions (MAGE), parameters wich are determined by continuous glucose monitoring (CGM). In our study glucose variability and MAGE were significantly higher in persons with type 1 diabetes, in women and in insulin treated persons. They were correlated with haemoglobin A1c values. They did not vary significantly after 3 months since the first CGM.