GLUCOSE VARIABILITY IN PERSONS WITH DIABETES EVALUATED BY CONTINUOUS GLUCOSE MONITORING

  • Andreea Morosanu
  • Magdalena Morosanu
  • Silviu Valeriu Pasniciuc
  • Monica Negrean
Keywords: type 1 and type 2 diabetes, glucose variability, mean amplitude of glucose excursions, continuous glucose monitoring

Abstract

Blood glucose level is the main indicator of diabetes control. It is related to diabetes evolution and appearance of chronic complications. Daily and/or postprandial glucose fluctuations induce oxidative stress and endothelial dysfunction in a higher extent than sustained hyperglycemia. Glucose excursions can be expressed by glucose variability and by mean amplitude of glucose excursions (MAGE), parameters wich are determined by continuous glucose monitoring (CGM). In our study glucose variability and MAGE were significantly higher in persons with type 1 diabetes, in women and in insulin treated persons. They were correlated with haemoglobin A1c values. They did not vary significantly after 3 months since the first CGM.

Published
2010-12-15
How to Cite
Morosanu, Andreea, Magdalena Morosanu, Silviu Pasniciuc, and Monica Negrean. 2010. “GLUCOSE VARIABILITY IN PERSONS WITH DIABETES EVALUATED BY CONTINUOUS GLUCOSE MONITORING”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 17 (4), 239-48. https://rjdnmd.org/index.php/RJDNMD/article/view/355.
Section
Original Research Articles