LIPID PROFILE IN PATIENTS WITH STROKE: DIABETICS AND NO DIABETICS

Abstract

Background: Dyslipidaemia is one of the cardiovascular risk factors, but the association with stroke is not as strong as with heart disease. Diabetic patients who suffered a stroke have hypertension and dyslipidaemia in a higher percentage than nondiabetics.

Objective: we explored the status of lipid profile in patients with diabetes and without diabetes with stroke. Research design and methods: the study was conducted on two lots that included 228 subjects; lot 1 - 136 diabetic patients and stroke recently installed; lot 2 - 92 patients without diabetes but stroke recently installed, hospitalized in the eurologic Department of the County Emergency Hospital Valcea during 2006-2008.

Results: The average plasma cholesterol was significantly increased in subjects with diabetes and ischaemic stroke compared with nondiabetics (233.28 ± 47.81 mg / dl vs. 215.74 ± 36.79 mg / dl, p = 0.01 *). Hipertrigliceridemia was found in diabetic subjects with ischaemic stroke (199.07 ± 124.03 mg / dl), but not in nondiabetic subjects with ischemic stroke (129.21 ± 64.07 mg / dl) between the two lots being statistically significant difference (p <<0.05). The average values of LDL-chol. were increased in diabetic subjects and ischemic stroke vs. nodiabetics (131.91 ± 35.24 mg / dl vs. 121.38 ± 20.94 mg / dl) with a statistically significant difference p= 0.026.

Conclusions: dyslipidaemia is found to be the risk factor for ischemic stroke in diabetic subjects, with statistically significant differences compared to nondiabetics. HDL-cholesterol was found as a protective factor for haemorrhagic stroke in nondiabetic subjects.