THE PROGRESSES IN TYPE 2 DIABETES GENETIC ARE EXPLOSIVE, BUT WITH MINIMAL EFFECT ON THE PREDICTION OF THE DISEASE

Abstract

Diabetes mellitus is one of the diseases that can become manifest from the first up to the last day of life1. The incidence of the disease however can vary widely between age groups: from 0,1 cases/100.000 persons/year (during the first year of life) to higher than 500 cases/100.000 persons/year (for the age group 60-70 years). Each of the various diabetes phenotypes described to date can be more frequent in a particular age group but can be encountered however (even if with lower frequency) in any age group. The only notable exception is the neonatal diabetes which,bydefinitionhasitsonsetinthefirst6 months after birth. Gestational diabetes mellitus has also, by definition, a precise positioning but its onset depends on the age at the time of pregnancy.