THE DYSMETABOLIC SYNDROME – DEFINITION, HISTORY, COMPONENTS

Abstract

Some researchers tend to think of the dysmetabolic syndrome as being the most important medical problem of the 21st century beginning.
The dysmetabolic syndrome is rather difficult to estimate because of the numerous existing points of view regarding the elements needed for the diagnosis.
It isn’t about a singular disease, but an association of impairments that can appear simultaneously or gradually in the same individual, caused by associating the genetic and environmental factors (+ lifestyle) with the insulin - resistance, considered as the fundamental pathogenic component.
The first definition of the metabolic syndrome (MS) was formulated in 1998 by a group of researchers from OMS (the group being concerned with studying diabetes). It made precise the fact that the syndrome is defined by the presence of type II diabetes mellitus or the altered tolerance to glucose combined with at least 2 other factors (hypertension, increased level of blood lipids, obesity and microalbuminuria).
Starting with that first definition (initial one) of the metabolic syndrome a range of alternative definitions was suggested. The most widely accepted definition was formulated by EGIR (European Group for the Study of Insulin Resistance) and NCEP (USA National Cholesterol Education Panel).