METABOLIC DISORDERS IN PATIENTS WITH HIV

  • Florentina Radu
  • Raluca Elena Jipa
  • Emilia Rusu
  • Raluca Cursaru
  • Ramona Drăguț
  • Daniela Stegaru
  • Andra Gabriela Gheorghiță
  • Gabriela Radulian
Keywords: insulin resistance, metabolic disorders, dyslipidemia, diabetes

Abstract

Human Immunodeficiency Virus (HIV) infection and subsequent antiretroviral therapy (ART) are known to be related to different metabolic disorders. Although ART decreased HIV-associated mortality and morbidity, mortality rates in patients with HIV and ART are 3 to 15 higher than those in the general population. More than 50% of the mortality is due to diseases like: diabetes mellitus (DM), hypertension, cardiovascular diseases (CVD), chronic renal disease and complications following bone fractures. In patients with HIV the metabolic disorders are mainly caused by mithocondrial toxicity, a side effect of ART, and they are represented by: dyslipidemia, lipoatrophy, insulin resistance and diabetes mellitus.

Published
2016-12-15
How to Cite
Radu, Florentina, Raluca Jipa, Emilia Rusu, Raluca Cursaru, Ramona Drăguț, Daniela Stegaru, Andra Gheorghiță, and Gabriela Radulian. 2016. “METABOLIC DISORDERS IN PATIENTS WITH HIV”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 23 (4), 397-401. https://rjdnmd.org/index.php/RJDNMD/article/view/73.
Section
Review Articles