METABOLIC INTERPLAY OF HEPATIC ENZYMES – A CASE REPORT

  • Anca Ungurianu
  • Rucsandra Dănciulescu Miulescu
  • Denisa Margină
Keywords: AST, ALT, exercise, cardiometabolic risk

Abstract

Introduction: Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are part of the routine blood tests and are usually used to assess liver or cardiac status. The most common disturbances are the mildly risen levels which are correlated with hepatic dysfunction and entail a wide variety of etiologies: viral, toxic, drug or are lifestyle related. Case report: Routine blood tests revealed high AST and ALT levels in an otherwise healthy 40-years-old male. After a series of supplementary tests the cause remained undetermined, so more attention was paid to the patient’s daily routine. Recently he started an intense training program which led to extensive muscle damage causing an elevation of plasma transaminases’ levels. Discussion: When dealing with a rise in AST and ALT levels in asymptomatic patients, physicians must carefully consider all aspects, from family and personal history, infectious diseases or toxins to medication and lifestyle, in order to avoid unnecessary tests and incorrect diagnoses or treatments.

Published
2016-06-15
Section
Original Research Articles