Luteolin: protective effects against diabetes and diabetes associated complications

Luteolin and Diabetes

  • Chanky Mehta
  • Kriti Kushwaha
  • Jeena Gupta Lovely Professional University
Keywords: Luteolin, Phytochemical, Diabetes, Diabetic nephropathy, Reactive oxygen species


Diabetes is known to be associated with a deficiency of insulin affecting directly or indirectly other important parts of the human body. There are various forms of treatment in Ayurveda and other traditional medicinal systems which use naturally occurring compounds for the treatment of diseases. One such widely studied phytochemical is Luteolin. Luteolin is known to be present in a wide variety of plant species, especially edible plants like carrots and cucumbers. Luteolin belongs to the group of flavonoids having its unique properties and is known to inhibit pro-inflammatory cytokines. The cellular actions and properties make luteolin a potent anti-diabetic compound. Luteolin’s antioxidant function, together with its hypoglycemic ability, protects the pancreas and facilitates the secretion of insulin which makes it effective and important for medicinal studies. In this review, we will focus upon the ability of luteolin to treat diabetes and its related complications.

How to Cite
Mehta, Chanky, Kriti Kushwaha, and Jeena Gupta. 2021. “Luteolin: Protective Effects Against Diabetes and Diabetes Associated Complications”. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 28 (3), 303-10.